Game Theory: Ellie Is NOT Immune! (The Last of Us Part 2)

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The Last of Us franchise is a story of humanity trying to survive in the face of a virus turning people into fungus creatures that are not quite zombies. We learn early on in the first game that Ellie is immune, perhaps even the only immune person there is. This makes her invaluable to those trying to find a cure. Except, I think she may not be immune. The second game shows a lot of evidence that something else may be going on with Ellie. Something that may tell us the future direction of this story and the future of Ellie. 

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#TheLastofUs #TheLastofUs2 #LastofUs #TheLastOfUsPart2 #TLOU #TLOU2 #Ellie #Joel #NaughtyDog #Theory #GameTheory  #MatPat

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Writer: Stephanie Patrick
Researcher: Zach Stewart
Editors: Dan “Cybert” Seibert, Koen Verhagen, and Josh Langman
Assistant Editor: AlyssaBeCrazy
Sound Editor: Yosi Berman


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  • it mutated inside her

    Brandon Martin July 23, 2020 6:55 pm Reply
  • How is Ellie the only one the entire world to get the “Healthy” strain? Yet everyone else dies from infected or spores.? There has to be more people like her at this point. Doesn’t really make sense.

    WHΞNWΞDIΞ July 23, 2020 6:55 pm Reply
  • so what your saying is Ellie Is Immune!

    Brandon Martin July 23, 2020 6:55 pm Reply
  • So just infect everyone

    Captain Wolf July 23, 2020 6:55 pm Reply
  • Didint watch yet, is she asymptomatic

    Captain Wolf July 23, 2020 6:55 pm Reply
  • Food theory reference in the start nice

    Nicholas Bredmund July 23, 2020 6:55 pm Reply
  • This was very interesting especially in my case as laboratory technicians. You don't have to be a doctor to understand this.

    ElizabethDarkon July 23, 2020 6:55 pm Reply
  • when you play the first game and then play the second one you notice the inconsistency I get that games are not supposed to be realistic but at least make it make sense lol

    35692Zz July 23, 2020 6:55 pm Reply
  • But she was bitten by a zombie with the bad fungus so she would have gotten the bad one. Debunked

    nathaniel baeza July 23, 2020 6:55 pm Reply
  • So if she has another strain of the fungi how did she get it? This is why I simply think she’s just really immune and not because all of the other stuff you explained. Because how did she get the other strain from the runner that bit her?

    SneakySweetSavage Gaming July 23, 2020 6:55 pm Reply
  • Shut up it’s a game it’s not real

    Gage G July 23, 2020 6:55 pm Reply
  • I'd believe it. How'd she go from not having to wear a gas mask in spores to needing one?

    Shaggy SmilesSRL July 23, 2020 6:55 pm Reply
  • Maybe the doctors doesn't take mycology

    Dhiyaulhaq Fikar Sahidin July 23, 2020 6:55 pm Reply
  • Wow… If you had been a doctor in the game, Abby would have still had a dad. Granted, a stupid dad who probably shouldn't be a doctor, but a dad none the less. 😀

    lnhal3 July 23, 2020 6:55 pm Reply
  • Dude naughty dog is not thinking that deep he proved that with last of us 2 that he doesn’t think that deep

    Rodney July 23, 2020 6:55 pm Reply
  • I just thought it was similar to the Lief situation in Bug Fables. This is a cool theory.

    Cadence _ July 23, 2020 6:55 pm Reply
  • I dont like that its probaly true but I would rather think that she is immune.

    TrashPanda July 23, 2020 6:55 pm Reply
  • Emm she was bite didn't change there go immune.

    King Zilla July 23, 2020 6:55 pm Reply
  • This reminds me of how vaccines are made…they injected cowpox on a kid to protect from smallpox

    Sergs Anairo July 23, 2020 6:55 pm Reply
  • Mr. Mat, Please check out Hello Neighbor 2! It's sooo epic so please, please, check it out! I watched FuzionZGamer's breakdown of the trailer and my theorist senses are tingleing! I sense lore in that trailer. I'm going to go get my theorybook, and start crafting my theory.

    KingBabyYoda'sLoyalFollower July 23, 2020 6:55 pm Reply
  • GAMER' S voice Matters !! sign the PETITION !! please we count on you!! imaginez les maisons d'édition et de creation de jeux video sur nextgen en PVP dans un monde ouvert en constante evolution (DLC mise a jour ) où vous pouvez choisir d'être un héro ou un vilain , non seulement en joueurs vs joueurs mais aussi dans le mode histoire du jeux!! une map qui serait destructible où vous pourrez utiliser des ascenseurs ,la mer,les rivières, les caves,les égouts sans avoir de chargement a l'ecran (exple: battlefield hardline), vous pourrez detruire des immeubles ou maisons ou lieux approprié pour des joueurs ou pnj!!
    Tous ces lieux ce reconstruiront des le lancement d'une nouvelle partie. Un mode histoire vous permettant de débloquer toutes les astuces de vos perso ou toutes les armes, gadget, tenues,armures et autres pour vos persos!! voila pourquoi les maisons d'édition de jeux ont besoin de nos idées afin que nous puissions élargir la possibilité de jouer ensemble dans desunivers de jeux innovante !! Signé ,vite, la Pétition !!
    Le crossplay console prend de plus en plus d'ampleur!! Grâce aux pétitions signé par des joueurs et non-joueurs du monde entier !! VOTRE VOIX COMPTE !!
    Alors élargissons les option multijoueurs (pas seulement en coop.) les maisons d'édition et de création de jeux video !! ne restons plus passif mais aidons les à faire encore mieux!! Le monde du jeu vidéo compte sur vous tous!! faites tourner cette petition au maximum afin d'augmenter les signatures !! pensez aux communautésde joueurs du monde entier!! merçi et que la force soit avec vous!!
    imagine the video game publishing and creation houses on nextgen in PVP in a constantly evolving open world (updated DLC) where you can choose to be a hero or a villain, not only in players vs players but also in the story mode of the games !! a map that would be destructible where you can use elevators, the sea, the rivers, the cellars, the sewers without having loading on the screen (ex: battlefield hardline), you can destroy buildings or houses or places suitable for players or PNJ !!
    All these places will rebuild from the launch of a new game. A story mode allowing you to unlock all the tips of your characters or all the weapons, gadgets, outfits, armor and others for your characters !! that is why game publishers need our ideas so that we can expand the possibility of playing together in innovative game worlds !! Signed, quickly, the Petition !!
    Console crossplay is becoming more and more important !! Thanks to petitions signed by players and non-players around the world !! YOUR VOICE COUNTS !!
    So let's expand the multiplayer options (not just in co-op.) Publishing houses and video game creation !! let's no longer remain passive but help them to do even better !! The world of video games is counting on you !! run this petition to the maximum to increase signatures !! think of player communities around the world !! thank you and may the force be with you !!
    プレイヤー対プレイヤーだけでなく、ヒーローでも悪役でも選択できる、常に進化するオープンワールド(更新されたDLC)で、PVPのnextgenのビデオゲームのパブリッシングおよびクリエーションハウスを想像してください。ゲームのストーリーモードで!!画面にロードせずにエレベーター、海、川、地下室、下水道を使用できる破壊可能なマップ(例:戦場のハードライン)、建物や家、またはプレーヤーまたはPNJ !!

    Pureiyā tai pureiyā dakedenaku, hīrō demo akuyaku demo sentaku dekiru, tsuneni shinka suru ōpunwārudo (kōshin sa reta DLC) de, PVP no nextgen no bideogēmu no paburisshingu oyobi kuriēshonhausu o sōzō shite kudasai. Gēmu no sutōrīmōdo de! ! Gamen ni rōdo sezu ni erebētā, umi, kawa, chikashitsu, gesuidō o shiyō dekiru hakai kanōna mappu (rei: Senjō no hādorain), tatemono ya ie, matawa purēyā matawa PNJ! ! Korera no basho wa subete, atarashī gēmu no kaishi kara sai kōchiku sa remasu. Kyarakutā no subete no hinto ya, kyarakutā no subete no buki, gajetto, ishō, yoroi nado o anrokku dekiru sutōrīmōdo! ! Kakushintekina gēmu no sekai de issho ni purei suru kanōsei o hirogeru tame ni, gēmupaburisshā ga watashitachi no aidea o hitsuyō to shite iru no wa sonotamedesu. Shomei, jinsoku ni, seigan-sho! ! Konsōru no kurosu purei wa masumasu jūyō ni natte imasu! ! Sekaijū no purēyā to hi purēyā ni yotte shomei sa reta seigan no okage de! ! Anata no koe no kazu! ! Soredewa, maruchipureiyā no opushon o kakuchō shimashou (kyōryoku purei dakede wa arimasen). Paburisshinguhausu to bideogēmu no sakusei! ! Mō judō-tekina mamade wa naku, karera ga yori yoi koto o suru no o tasukemashou! Bideogēmu no sekai wa anata ni kitai shite imasu! ! Kono seigan-sho o saidaigen ni jikkō shite shomei o fuyashite kudasai! ! Sekaijū no purēyākomyuniti o kangaete kudasai. Arigatō, soshite chikara ga anata to tomoni arimasu yō ni! !


    cedano371 July 23, 2020 6:55 pm Reply
  • you should make a podcast

    HAHAHA IM THE DIRECTOR July 23, 2020 6:55 pm Reply
  • Couldn't Elle bite someone and spread her immunity strain of cordyceps? Same way a bite from someone with one of the bad strains of cordyceps bites someone and spreads the bad virus?

    Ja Sa July 23, 2020 6:55 pm Reply

    zenslayer08 July 23, 2020 6:55 pm Reply
  • Ok i get what your saying but she was biten by someone that was infected so wouldnt that zombie have the same fungus as elli?

    Dawn S July 23, 2020 6:55 pm Reply
  • a game to play an old alpha

    Dusty The Fox July 23, 2020 6:55 pm Reply

    Mig July 23, 2020 6:55 pm Reply
  • World War Z flashback intensifies

    mancis July 23, 2020 6:55 pm Reply
  • Today is the 23. And I still dont know what's going on 😔

    Kari Specht July 23, 2020 6:55 pm Reply
  • Okay yeah i watch the entire video and he proved that ellie isnt imune and that she got the wrong type of cordyceps but…… did ellie get the wrong type if she was infected by a zombie who had the right type of cordyceps the zombie type of cordyceps and was bitten by the same zombie her friend got bit by and died and she is still alive can you explain that in a different video cuz im confused

    Jason Carter July 23, 2020 6:55 pm Reply
  • Matpat: Appears in Xbox showcase
    The showcase: Reveals Hello Neighbor 2

    Dark Arceus July 23, 2020 6:55 pm Reply
  • Ellie: gets bitten twice in the series and has absolutely nothing to show for it but a bite mark
    Game Theorists: "ShEs NoT ImMuNE"

    Avram Sanders July 23, 2020 6:55 pm Reply
  • Question
    She was bitten by a zombie ok that’s point 1
    If you say the cortasepts was in the zombie wouldn’t the zombie that bit Elle wouldn’t be a zombie that’s point 2
    And if the immune system doesn’t attack the bite how the zombie bite heal as the cortasepts starts growing from there, and left traces of the cortasepts that’s point 3
    If you agree with me coment

    Eaze_Abhi July 23, 2020 6:55 pm Reply
  • These thoeies are being whored out twice a week now theres gonna be another channel, hope he doesn't get burnt out!

    ELI BONHAM July 23, 2020 6:55 pm Reply
  • I wouldn't be surprised if MatPat's new channel was Book Theory, lol

    Albert July 23, 2020 6:55 pm Reply
  • No one is talking about how when it went to the yellow logo, the intro went faster than slower, is this a hint?

    BlackRøse July 23, 2020 6:55 pm Reply
  • Today is the Yellow day

    Tix_Bex July 23, 2020 6:55 pm Reply
  • Oooooooooooookkkkkkk MatPat usually your theories ARE pretty crazy, but seriously?

    EDIT: Ok, I get it now 🙂

    GameDevLegit July 23, 2020 6:55 pm Reply
  • Scientists and doctors seems totally stupid in Last of us universe.

    The Non-IITian July 23, 2020 6:55 pm Reply
  • Wow no 1 minute long intro yay.

    Just_Justin July 23, 2020 6:55 pm Reply
  • 7/23????

    Sparklyracer44 July 23, 2020 6:55 pm Reply
  • Game theory: she’s not immune
    Game theory at the end of the video: the thing she has makes her immune

    Ajar Raccoon July 23, 2020 6:55 pm Reply

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